公司產(chǎn)品僅供科研研究實驗,不得用于臨床!
商品詳情:
英文名稱:FRA10AC1
中文名稱:10號染色體開放閱讀框4抗體
別 名;Chromosome 10 open reading frame 4; F26C11.1 like; C10orf4; FRA10AC1 protein; Fragile site 10q23.3; PRO2972; Protein FRA10AC1; Rare folic acid type fragile site FRA(10)(q23.3) candidate gene 1; F10C1_HUMAN.
研究領(lǐng)域;細胞生物 免疫學 神經(jīng)生物學
抗體來源;Rabbit
克隆類型;Polyclonal
交叉反應(yīng);Human, (predicted: Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用;WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (石蠟切片需做抗原修復(fù))
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量;38kDa
細胞定位;細胞核
性 狀;Liquid
濃 度;1mg/ml
免 疫 原;KLH conjugated synthetic peptide derived from human C10orf4: 101-200/315
亞 型;IgG
純化方法;affinity purified by Protein A
緩 沖 液;0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件;Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事項;This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹;The protein encoded by this gene is a nuclear phosphoprotein of unknown function. This gene contains a tandem CGG repeat region within a CpG island that normally consists of 8-14 repeats but can expand to over 200 repeats. The repeat region is within the 5' UTR of some transcript variants, but is intronic to another variant. The expanded repeat allele is a fragile site and becomes hypermethylated, causing a reduction in gene expression. A disease phenotype has not been associated with expanded alleles. This gene is found within the rare FRA10A folate-sensitive fragile site. [provided by RefSeq, Dec 2016]
Subcellular Location:
Nuclear.
Tissue Specificity:
Ubiquitously expressed with higher expression in brain, heart, skeletal muscle, kidney and liver.